Basic Science Mentors

Genomic and Epigenetic Instability

Greg Rogers, PhD

Greg Rogers, PhD 
Associate Professor, Cellular and Molecular Biology

Research focus: Understanding cellular mechanisms that regulate centrosome duplication, nuclear organization, and genomic integrity.

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Eric Weterings, PhD

Eric Weterings, PhD 
Associate Professor, Radiation Oncology

Research focus: DNA repair mechanisms during carcinogenesis.

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 Nathan Ellis, PhD

Nathan Ellis, PhD
Associate Professor, Cellular and Molecular Medicine

Research focus: Genetic analysis of genomic instability in cancer susceptibility.

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Keith Maggert, PhD

Keith Maggert, PhD
Associate Professor, Cellular and Molecular Medicine

Research focus: Connection between epigenetic instability and chromosome damage.

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Anne Cress, PhD 

Anne Cress, PhD
Professor, Cellular and Molecular Medicine

Research focus: Molecular mechanisms of human cancer progression and metastasis and the regulation of cell surface adhesion molecules, called integrins.

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Cathy Smith, PhD 

Cathy Smith, PhD
Associate Professor, Pharmacology & Toxicology

Research focus: Epigenetic mechanisms of gene expression.

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 Justina McEvoy, PhD

Justina McEvoy, PhD
Assistant Professor, Molecular and Cellular Biology

Research focus: Regulation of differentiation programs during normal development and tumorigenesis in pediatric cancers.

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Guang Yao, PhD 

Guang Yao, PhD
Assistant Professor, Molecular and Cellular Biology

Research focus: Gene networks that control the life and death of cancer cells.

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Tumor Microenvironment

Andrew Kraft, MD

Andrew Kraft, MD 
Director, University of Arizona Cancer Center

Research focus: Prostate cancer and drug development.

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Noel Warfel, PhD

Noel Warfel, PhD
Assistant Professor, Cellular and Molecular Medicine

Research focus: Understanding the complex biological mechanisms that allow cancer cells to thrive in the hypoxic tumor microenvironment and developing new therapeutic strategies to oppose hypoxia-mediated therapeutic resistance.

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 Cindy Miranti, PhD

Cindy Miranti, PhD
Professor, Cellular and Molecular Medicine

Research focus: Defining the mechanisms by which cell adhesion and the tumor microenvironemtn promote prostate cancer progression and metastasis.

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Anne Cress, PhD

Anne Cress, PhD
Professor, Cellular and Molecular Medicine

Research focus: Molecular mechanisms of human cancer progression and metastasis and the regulation of cell surface adhesion molecules, called integrins.

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Cathy Smith, PhD 

Cathy Smith, PhD
Associate Professor, Pharmacology & Toxicology

Research focus: Epigenetic mechanisms of gene expression.

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Donna Zhang, PhD

Donna Zhang, PhD
Professor, Pharmacology & Toxicology

Research focus: Mechanistic studies of the Nrf2/Keap1 signaling pathway that regulates antioxidant responses in arsenic-induced toxicity and carcinogenesis.

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Kirsten Limesand, PhD

Kirsten Limesand, PhD
Professor, Nutritional Sciences

Research focus: Radiation-induced salivary gland dysfunction, mechanisms of damage, clinical prevention measures, and restoration therapies.

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Gus Mouneimne, PhD

Gus Mouneimne, PhD
Assistant Professor, Cellular and Molecular Medicine

Research focus: Understanding how cytoskeletal architecture regulates cancer metastasis.

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Cancer Prevention and Control

Cyndi Thomson, PhD, RD

Cyndi Thomson, PhD, RD 
Professor, Public Health

Research focus: Dietary intervention in breast and ovarian cancer survivors, behavioral interventions for weight control and metabolc regulation.

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Janet Funk, MD

Janet Funk, MD
Professor, Medicine

Research focus: Turmeric dietary supplements as adjuvant therapeutics for the prevention of breast cancer bone metastases.

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 Karen Hastings, MD, PhD

Karen Hastings, MD, PhD
Associate Professor, Immunobiology

Research focus: Anrigen processing and control of T cell responses in skin cancer and autoimmunity.

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Sherry Chow, PhD

Sherry Chow, PhD
Research Professor, Medicine

Research focus: Development of cancer chemopreventive agents, and biochemical and molecular biomarkers for evaluation of cancer risk and drug efficacy.

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Donato Romagnolo, PhD

Donato Romagnolo, PhD
Professor, Nutritional Sciences

Research focus: Bioactive food components as epigenetic regulators of expression gees involved in cancer and inflammation.

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George Wondrak, PhD

Georg Wondrak, PhD
Associate Professor, Pharmacology & Toxicology

Research focus: Oxidative and proteotoxic stress in skin carcinogenesis and solar photodamage.

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Developmental Therapeutics and Clinical Trials

Denise Roe

Denise Roe, DrPH
Professor, Epidemiology and Biostatistics

Research focus: Statistical expertise in longitudinal data, pharmacokinetic studies, clinical trials, and translational research.

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Daruka Mahadevan, MD, PhD

Daruka Mahadevan, MD, PhD 
Professor, Medicine

Research focus: Discovering novel therapeutic targets and drug design.

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Bill Montfort, PhD

Bill Montfort, PhD
Professor, Chemistry and Biochemistry

Research focus: Nitric oxide signaling mechanisms.

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 William Cance, MD

William Cance, MD
Deputy Director, UACC-Phoenix

Research focus: Diagnosis and treatment of thyroid and parathyroid diseases, including thyroid cancer.

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Steffan Nawrocki, PhD

Steffan Nawrocki, PhD
Associate Professor, Medicine

Research focus: Oncolytic reovirus for cancer therapy, enhancin proteasome inhibitor-induced apoptosis, and autophagy in cancer progression and drug resistance.

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Jennifer Carew, PhD

Jennifer Carew, PhD
Associate Professor, Medicine

Research focus: Drug discovery, anticancer agents and mechanisms of drug resistance.

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Protul Shrikant, PhD

Protul Shrikant, PhD
Professor, Immunobiology

Research focus: Anti-tumor immunity

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Early Cancer Detection and Imaging

Diego Martin, MD, PhD

Diego Martin, MD, PhD
Professor, Medical Imaging and Biomedical Engineering

Research focus: Development of MRI technologies for targeted oncology and translplantation.

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Srinivasan Vedantham, PhD

Srinivasan Vedantham, PhD
Professor, Medical Imaging

Research focus: Design, development and clinical translation of novel x-ray imaging systems and imaging techniques focused on oncological and interventional imaging.

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 Andrew Karellas, PhD

Andrew Karellas, PhD
Professor, Medical Imaging

Research focus: Breast cancer imaging.

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Jennifer Barton, PhD

Jennifer Barton, PhD
Director, Bio5 Institute and Professor, Biomedical Engineering

Research focus: Breast cancer imaging.

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Tumor Viruses and Immunology

Manny Katsanis, MD

Manny Katsanis, MD
Professor, Pediatrics

Research focus: Enhancing anti-leukemia activity in hematopoietic cell transplantation and chemo-immuno-therapeutic strategies that promote anti-tumor immne responses.

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Sam Campos, PhD

Sam Campos, PhD
Assistant Professor, Immunobiology

Research focus: Molecular mechanisms through which HPVs infect and attain persistence in host epithelium.

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 Felicia Goodrum, PhD

Felicia Goodrum, PhD
Associate Professor, Immunobiology

Research focus: Mechanisms of human cytomegalovirus latency.

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Deepta Bhattacharya, PhD

Deepta Bhattacharya, PhD
Associate Professor, Immunobiology

Research focus: Molecular approaches to direct B cell differentiation to establish immunity to infectious disease, and stem cell differentiation for regenerative medicine.

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Michael Kuhns, PhD

Michael Kuhns, PhD
Associate Professor, Immunobiology

Research focus: T-cell signaling and the balance between tolerance of self-antigens and protective immunity against pathogenic infection.

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Protul Shrikant, PhD

Protul Shrikant, PhD
Professor, Immunobiology

Research focus: Anti-tumor immunity

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Megha Padi

Megha Padi, PhD
Assistant Professor, Molecular and Cellular Biology

Research focus: Computational approaches to integrate genomic "big data" and model how cellular networks are functionally altered by disease.

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Tumor Progression and Metastasis

Megha Padi

Megha Padi, PhD
Assistant Professor, Molecular and Cellular Biology

Research focus: Computational approaches to integrate genomic "big data" and model how cellular networks are functionally altered by disease.

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Andrew Paek

Andrew Paek, PhD
Assistant Professor, Molecular and Cellular Biology

Research focus: Cancer cell responses to chemotherapy treatment.

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Joyce Schroeder, PhD

Joyce Schroeder, PhD
Professor, Molecular and Cellular Biology

Research focus: Breast cancer progression and invasion.

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Justina McEvoy, PhD

Justina McEvoy, PhD
Assistant Professor, Molecular and Cellular Biology

Research focus: Regulation of differentiation programs during normal development and tumorigenesis in pediatric cancers.

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 Gus Mouneimne, PhD

Gus Mouneimne, PhD
Assistant Professor, Cellular and Molecular Medicine

Research focus: Understanding how cytoskeletal architecture regulates cancer metastasis.

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Andrew Capaldi, PhD

Andrew Capaldi, PhD
Associate Professor, Molecular and Cellular Biology

Research focus: Signaling pathways and transcription factors in a cell that are organized into circuits.

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Curtis Thorne, PhD

Curtis Thorne, PhD
Assistant Professor, Cellular and Molecular Medicine

Research focus: Combing chemical biology amd computer vision approaches to discover cellular communication mechanisms controlling cell fate, self-organization and disease progression of regenerative tissues.

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Jean Wilson, PhD

Jean Wilson, PhD
Professor, Cellular and Molecular Medicine

Research focus: Establishment and maintenance of the integrity of the intestine thruogh the regulation of membrane trafficking and the apical plasma membrane domain.

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Kirsten Limesand, PhD

Kirsten Limesand, PhD
Professor, Nutritional Sciences

Research focus: Radiation-induced salivary gland dysfunction, mechanisms of damage, clinical prevention measures, and restoration therapies.

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Pascale Charest, PhD

Pascale Charest, PhD
Assistant Professor, Chemistry and Biochemistry

Research focus: Signal transduction pathways and molecular mechanisms controlling directed cell migration, or chemotaxis, in eukaryotic cells.

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Timothy Bolger, PhD

Timothy Bolger, PhD
Assistant Professor, Molecular and Cellular Biology

Research focus: Function and regulation of a family of RNA helicases and RNP remodeling enzymes termed the DEAD-box proteins.

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Charles Wolgemuth, PhD

Charles Wolgemuth, PhD
Professor, Physics and Molecular and Cellular Biology

Research focus: Mechanisms cells use to produce the force necessary to create and maintain their shape, grow, and move.

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Genetic Risk Factors

Christina Laukaitis, MD, PhD

Christina Laukaitis, MD, PhD
Associate Professor, Medicine

Research focus: Individual risk assessment and counseling to develop a plan for treating neoplasia before metastatic cancer develops in people at high risk because of genetic factors.

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Nathan Ellis, PhD

Nathan Ellis, PhD
Associate Professor, Cellular and Molecular Medicine

Research focus: Genetic analysis of genomic instability in cancer susceptibility.

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Akinlolu Ojo, MD, PhD, MBA

Akinlolu Ojo, MD, PhD, MBA
Professor, Medicine

Research focus: Chronic kidney disease and kidney transplantation research and clinical care with a focus on health disparities.

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Cancer Pain

Frank Porreca, PhD

Frank Porreca, PhD
Professor, Pharmacology

Research focus: Neurobiology of pain.

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Todd Vanderah, PhD

Todd Vanderah, PhD
Professor, Pharmacology

Research focus: Mechanisms and pharmacology of acute and chronic models of pain; endogenous opioid systems; sensory neural systems; opioid tolerance; antinociceptive synergy between cannabinoids and opioids.

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 Patrick Mantyh, PhD, JD

Patrick Mantyh, PhD, JD
Professor, Pharmacology

Research focus: Cancer, cancer pain and non-malignant bone pain, stem cells and skeletal health in disease and aging.

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Tally Largent-Milnes, PhD

Tally Largent-Milnes, PhD
Research Assistant Professor, Pharmacology

Research focus: Pathological mechanisms and therapeutic targets for migraine headache and chronic neuropathic pain.

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Cancer Biomarkers

Cyndi Thomson, PhD, RD

Cyndi Thomson, PhD, RD
Professor, Public Health

Research focus: Dietary intervention in breast and ovarian cancer survivors, behavioral interventions for weight control and metabolic regulation.

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Sherry Chow, PhD 

Sherry Chow, PhD
Research Professor, Medicine

Research focus: Development of cancer chemopreventive agents, and biochemical and molecular biomarkers for evaluation of cancer risk and drug efficacy.

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Bernard Futscher, PhD

Bernard Futscher, PhD
Professor, Pharmacology & Toxicology

Research focus: Epigenomic dysfunction that drives human cancer.

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